EXOone M. haemolytica serotypes A1 + A2 + A6

Description

Mannheimia haemolytica is a primary bacterial agent associated with Bovine Respiratory Disease, but also contributes to pneumonia in domestic sheep and wild ruminants. M. haemolytica was reclassified as its own species with 12 of the 17 original P. haemolytica capsular serovars renamed as Mannheimia haemolytica (1, 2, 5, 6, 7, 8, 9, 12, 13, 14, 16, and 17).
Mannheimia haemolytica serotypes 1, 2, and 6 are the most prevalent worldwide. In cattle, serotypes 1 and 6 are commonly recovered from the lungs of diseased. In domestic sheep, disease is primarily associated with serotype 2 strains but a broad range of serotypes are recovered from ill animals.
Several methods for serotyping have been used to differentiate M.haemolytica serotypes such as indirect hemagglutination or slide agglutination. The development of a qPCRbased assay to identify serotype would eliminate the use of laboratory animals and eliminate associated subjectivity of agglutinationbased assays.