EXOone Clostridium novyi type A and B

Description

Clostridium novyi is an anaerobic Gram-positive bacterium widely distributed in soil as highly resistant spores. Type A and type B strains differ in toxin production but both are relevant in livestock infections.
These organisms are associated with severe diseases such as gas gangrene (type A) and infectious necrotic hepatitis or “black disease” (type B), characterized by rapid toxemia and high mortality. Infection is often linked to predisposing factors such as tissue damage or parasitic migration and can lead to significant economic losses.
Conventional detection based on culture may be limited by strict anaerobic requirements and rapid disease progression. Real-time PCR enables rapid, sensitive and specific detection of C. novyi DNA directly from clinical samples, supporting analytical detection and monitoring.