EXOone BVDV 2 (Pestivirus B)

Description

Bovine viral diarrhea virus (BVDV) is a ruminant pestivirus that causes important economic losses in cattle farming worldwide. BVDV strains are divided into two different genotypes known as BVDV type 1 (BVDV-1) and BVDV type 2 (BVDV-2), with different sub-genotypes within these two types. Cattle can be infected by both BVDV genotypes resulting in reproductive, enteric and respiratory disorders. Clinical presentations range from mild subclinical in immuno-competent cattle to highly fatal disorders such as hemorrhagic syndrome, associated with infection with virulent BVDV-2 strains.
Virus isolation, serological and molecular techniques have been used for the detection and identification of genotypes and sub-genotypes of BVDV, but recently, real time RT-PCR assays have provided a higher sensitivity and specificity for the identification of these pestivirus.